Science trying to science this thing Preliminary results show promise in treating critically ill patients As the debate rages about the viability of convalescent plasma (plasma extracted from those who are recovering from coronavirus (COVID-19), a paper published in the Journal of American Medical Association has hit a home run for a possible treatment methodology. At a time when the world is grasping at straws for treatment methods, every positive outcome raises hope. Though the study has a very small cohort, five patients, critically ill with COVID-19, the preliminary results are said to be promising, by experts across the world. In a paper authored by Chinese scientists Chenguang Shen, Zhaoqin Wang, Fang Zhao, et al, it has been argued that the ‘preliminary findings raise the possibility that convalescent plasma transfusion may be helpful in the treatment of critically ill patients with COVID-19 and ARDS, but this approach requires evaluation in randomised clinical trials.’ While the cohort is small, there is less scepticism about the study results, experts argue, because the method (convalescent plasma) has worked well for other conditions Five critically ill patients with confirmed COVID-19 and with acute respiratory distress syndrome (ARDS), who also had the following — severe pneumonia with rapid progression and continuously high viral load despite antiviral treatment; and mechanical ventilation — were chosen for treatment with convalescent plasma transfusion. The plasma was drawn from five patients, who had recovered from COVID-19. The study was conducted at the infectious disease department, Shenzhen Third People’s Hospital in Shenzhen, China, from January 20, 2020, to March 25, 2020. Clinical outcomes improved dramatically post the intervention, the authors record They added: “Following plasma transfusion, body temperature normalised within 3 days in 4 of 5 patients, the Sequential Organ Failure Assessment score decreased, and the ratio that determines severity of ARDS increased within 12 days (172-276 before and 284-366 after). Viral loads also decreased and became negative within 12 days after the transfusion ARDS resolved in four patients 12 days after transfusion, and 3 patients were weaned from the ventilator within two weeks. Of the 5 patients, 3 have been discharged from the hospital and 2 are in a stable condition 37 days after transfusion, the paper recorded. ‘Encouraging data’ Vincent Rajkumar, haematologist and oncologist at Mayo Clinic, in Minnesota, says: “This study provides encouraging data that treatment with plasma collected from patients who have recovered from COVID 19 treatment can work. Since collecting, storing, and giving plasma is routine process for blood banks, it’s something that is easy to do. It will also get increasingly easier as there are more and more people who recover from COVID-19.” Meanwhile, the British Medical Journal has reported that the U.S. FDA has approved the use of plasma from recovered patients to treat people who are critically ill with COVID-19, ‘provided that doctors get approval over the telephone.’ The article added: The method has been used in the past to treat diseases such as polio, measles, and mumps, in the 1918 flu epidemic
Ever occurred to you their models are wrong? Models are notorious for being wrong. Number of deaths went down yesterday from over 500 to 250. Their graph looks just like the climate change graphs, predicts catastrophe, but the observed data is following the lower limit. Their model has us hitting 2500 deaths per day, Italy never even hit those kinds of numbers. Our situation is driven by N.Y. with a population 1/3 of Italy. So, even if you throw in the rest of the US to account for the other 2/3 of Italy, we will never go over 1000 deaths per day, and frankly, I’ll be surprised if we hit even that. Not saying it can’t happen, but not very likely. Put on top of that, FDA has approved HCQ + AZ for emergency treatment, so, we may be at our top death rate already, and let’s face it, deaths are the only real concern. Average stay in hospital is significantly shortened with the drugs, and that frees up beds, and vents, and everything else. I would suggest you pull your head out of Trumps ass ... you might see a different picture.
Yea, I said 500-1000 because at the time there were less than 4K global deaths.... Further, if you simply have COVID19 in your system and die of a heart attack, they count it as a COVID19 death. No, I will not shut up. All you have been doing is bitching non stop about Trump not doing enough yet never say what it is exactly he should have been doing. Further, I stand by my statement that blowing up our economy will destroy more lives than COVID19. That isn't partisan, its just a fact. Why must you lie?
I saw that one too. Also saw a tweet from a guy who claims to work "in a medical examiner's office" and says in that area (didn't say where), murder victims are being reported as COVID-19 deaths if the virus is present. Take that FWIW, and I see some people defending it, arguing that its necessary to inflate the stats to scare people into taking it seriously. I'm all for giving the stupid among us a smack on the head, but will it be worth it in the long run if we find out afterward that we've been manipulated? Talking about the trust factor, both in government and media, neither of which is very strong to begin with.
So as Fauci said the models are the best available for predictions and it’s best to prepare for the worst and hope for the best. It will be great if what you hope for happens.....but it may be much worse. What do you do if you’re not prepared. So I saved your last comment because I’m confused. Usually when some says that it’s a criticism for being too supportive. Are you saying I support Trump too much????
Now here’s a post with no attribution and no support that is being taken as gospel. I would say that’s believing in a hoax.
@LSUpride123 your comment about balancing the damage the disease creates vs the damage caused by the isolation and quarantine is an excellent debate point. I think it will take a delicate balance between the two. Too much suppression and we kill it yet not enough can cause so much disruption that it’s killed as well. As I said early on our economy is balanced on a fairly fine line. Without transportation we starve so we can’t choke it off too long. I think Trump is handling it as well as can be done. It’s important that we have hope that it will end.
If you're not up on your text acronyms, I specifically said, take it For What Its Worth, which, without attribution, may be nothing.